The interpretation framework behind every Mosaic insight.
A comprehensive, gene-by-gene interpretation framework that lives inside your provider dashboard: watermarked, role-gated, and updated as the science evolves.
What it is
A living reference, not a PDF.
The Provider Guide is an interactive web reference inside your Mosaic dashboard. It cross-references your client’s results against the full interpretation framework in real time — so while you review a report, the Guide shows you what to look at and how to think about it.
Each of the 108 insights is covered in depth: gene mechanism, variant-level significance with tier rankings, phenotype patterns to watch for, the questions to ask in consultation, intervention frameworks (cofactors, dietary modulators, supplement forms), and escalation triggers.
Access is gated behind an approved provider account, and each view is watermarked with your name and license — a credentialed-provider resource, not a public download.
What’s inside
Nine sections. 108 insights. In-depth coverage.
The Guide mirrors the structure of the Genomic Lifestyle Optimization Report, so when your client’s report shows a finding, the interpretation is one click away.
Section 01Appetite and Eating Behaviors
Why Certain Foods Feel Impossible to Resist (and What Your Genes Have to Do With It)
Section 02Metabolism and Digestion
The Real Reason Some Foods Love You Back — While Others Quietly Sabotage You
Section 03Macronutrients and Metabolic Optimization
There is no one-size-fits-all "perfect diet." Only the one your metabolism was built for.
Section 04Micronutrients and Strategic Supplementation
Which vitamins your body actually needs, and which ones you're just expensively excreting.
Section 05Sleep Optimization and Circadian Health
Fighting your chronotype is the biological equivalent of swimming upstream.
Section 06Detoxification Pathways
How fast (or slowly) you actually clear coffee, meds, alcohol, and pollution.
Section 07Toxin Sensitivities
Some immune systems shrug off mold. Others mount a full response to trace amounts. Yours does one of those.
Section 08Athletic Performance
Power athlete trapped in an endurance body (or vice-versa)?
Section 09Hormone Health
How your body actually produces, converts, and responds to hormones.
Expanding with each new report
The Provider Guide grows with the Mosaic Reports library. As the Pre-Conception, GLP-1, and SNP-panel reports launch through 2026, the Guide adds matching coverage — gene mechanism, phenotype patterns, intervention frameworks — for each. Existing provider accounts get the new sections automatically.
Browse the Reports librarySubstantial depth, without protocol-prescribing.
The Guide is built to support your judgment, not replace it. It surfaces the science and the relevant patterns; you decide how to apply them with your specific client.
Gene mechanism breakdown
For each insight: the gene name, the enzyme or protein it encodes, the pathway it sits in, and how the mechanism produces the phenotype.
Variant significance with tier ranking
Specific allele effects mapped to tier-1 / tier-2 / tier-3 significance, so you know where the meaningful findings sit.
Consultation question scripts
Specific questions to ask during consultation, organized per insight. Translates "this variant does X" into "ask about Y".
Intervention frameworks
Cofactor support, dietary modulators, lifestyle leverage, and supplement-form guidance. Mechanism-led, not generic protocol.
Red-flag screening + referrals
When a finding warrants escalation, the Guide flags it and points you to the specialty. A built-in safety scaffold.
Cross-referenced pathways
Most findings worth acting on span several genes (vitamin D activation through GC, CYP2R1, and VDR; thyroid conversion through DIO1 and DIO2). The Guide maps the full pathway per insight, so you see what an isolated reading would miss.
Who it’s for
Practitioners integrating genomics into precision-health practice.
Functional & integrative medicine
Bringing genomic context into nutrition, sleep, detox, and hormone work.
Longevity & human performance
Practitioners who want defensible, clinical-grade genomic data underneath their optimization work.
Health & epigenetics coaches
Coaches who facilitate testing for clients and want a structured reference to support consultations.
Endocrinology, GI & sports medicine
Clinicians looking for variant-level context to layer on top of standard panels.
How access works
Three steps. One business day, typically.
- 01
Create your free provider account
Tell us about your practice and credentials. The signup form lives inside the Mosaic app and takes about three minutes.
- 02
Account review and approval
Typically same business day. Once approved, the Provider Guide opens inside your dashboard alongside wholesale kit ordering.
- 03
Use it alongside client reports
Open the Guide next to a client report. It surfaces the insights with the most notable findings and walks you through interpretation per insight.
Become a Mosaic Biodata Institute certified epigenetics coach.
The Institute is a structured certification program for practitioners who want lifestyle genomics as a core practice modality. Provider Guide access is included.