When your labs say normal but you don’t feel normal.
Thyroid hormone conversion, estrogen metabolism, and progesterone receptor sensitivity vary across genotypes. Mosaic reads the genes that shape those pathways, so the symptoms behind “labs are normal” start to have a real explanation.
T4 → T3 conversion: DIO1, DIO2 — how efficiently your body activates thyroid hormone.
Estrogen metabolism: CYP1A1, CYP1B1, COMT, the SULT and UGT families — which pathway your estrogens prefer to take, and how cleanly they clear.
Receptor sensitivity: ESR1, ESR2, and progesterone receptor — does your tissue respond loudly or quietly to the hormones you already have?
A complete read of every system, including the metabolism-and-digestion and detoxification pathways — both deeply interconnected with hormone health.
Defensible in clinical conversation: built and refined inside 10+ years of clinical practice at Apeiron Center.
The missing data behind “normal labs, abnormal symptoms.”
Mosaic’s Hormone Health report scores your variants across T4→T3 conversion, estrogen-metabolism pathways, and receptor sensitivity. Each finding shows up as a personalized dark card with a color marker and practical guidance you can take to your provider.
See a real report