Most consumer DNA tests read 0.02% of your genome. Mosaic reads 100%.
A SNP chip samples about 600,000 positions. Whole-genome sequencing reads all 3 billion, at 30× depth, in an accredited clinical lab. Here is what that changes.
Mosaic vs a typical consumer DNA test.
| Feature | Mosaic Biodata | Consumer DNA tests |
|---|---|---|
| How much of your DNA is read | 100%: every chromosome, every gene, at 30× depth. | About 0.02%: a SNP chip samples around 600,000 pre-selected positions. |
| Health insights | 108 insights across nine areas of your health, plus deep-dive reports on the same genome. | Ancestry plus a limited set of traits, depending on tier. |
| Lab standard | CLIA-, COLA-, CAP-, and AABB-accredited U.S. lab partner. | High-throughput consumer genotyping; not a clinical workflow. |
| Raw data ownership | Lifetime ownership of your full raw genome. Download anytime. | Raw SNP data downloadable; no whole-genome data generated. |
| Future re-analysis | Every future report runs on the data you already have. | Limited to the SNPs the chip captured at purchase time. |
| Pricing model | One-time purchase. No subscription. | Lower entry price; subscription for the deeper features. |
| Privacy | Never sold, shared, licensed, or monetized. | Consumer privacy policy; opt-in research participation common. |
How much of your DNA is read
Mosaic Biodata
100%: every chromosome, every gene, at 30× depth.
Consumer DNA tests
About 0.02%: a SNP chip samples around 600,000 pre-selected positions.
Health insights
Mosaic Biodata
108 insights across nine areas of your health, plus deep-dive reports on the same genome.
Consumer DNA tests
Ancestry plus a limited set of traits, depending on tier.
Lab standard
Mosaic Biodata
CLIA-, COLA-, CAP-, and AABB-accredited U.S. lab partner.
Consumer DNA tests
High-throughput consumer genotyping; not a clinical workflow.
Raw data ownership
Mosaic Biodata
Lifetime ownership of your full raw genome. Download anytime.
Consumer DNA tests
Raw SNP data downloadable; no whole-genome data generated.
Future re-analysis
Mosaic Biodata
Every future report runs on the data you already have.
Consumer DNA tests
Limited to the SNPs the chip captured at purchase time.
Pricing model
Mosaic Biodata
One-time purchase. No subscription.
Consumer DNA tests
Lower entry price; subscription for the deeper features.
Privacy
Mosaic Biodata
Never sold, shared, licensed, or monetized.
Consumer DNA tests
Consumer privacy policy; opt-in research participation common.
What 100% gets you.
Rare variants the chip never looked at.
A chip reads the positions its maker chose. Sequencing reads every position, so the variants that matter for you are there whether or not they were common enough to make a chip.
Reanalysis when the science moves.
New report, same genome. Every deep-dive report runs on the file you already have. No new sample.
A raw genome you own.
Standard formats, downloadable any time, usable anywhere else that reads them.
Interpretation built in a clinic.
The framework behind every insight was refined client by client for more than a decade at Apeiron Center.
A SNP chip is a thumbnail. Sequencing is the full image.
A SNP chip is a cost shortcut: pre-choose about 600,000 of the most commonly varied positions in the human genome and read just those, cheaply. The chip cannot tell you what is at the other 99.98% of your DNA.
For ancestry estimates and well-studied common traits, the chip is enough. For interpretation that handles rare variants, structural variants, and new science as it lands, you need every position read, not inferred. That is what sequencing at 30× depth gives you.
| Feature | Mosaic sequencing (30×) | SNP arrays (consumer chips) |
|---|---|---|
| What the technology reads | All 3 billion base pairs across all chromosomes. | About 600,000 pre-selected SNP positions (about 0.02% of the genome). |
| How positions are selected | No selection. Every base is sequenced. | The manufacturer decides which SNPs the chip captures at design time. |
| Read depth | 30×: each position is read about 30 times, so a variant call is reliable. | Single-pass hybridization signal; not depth-based. |
| Variant types detected | SNVs, indels, structural variants, copy-number variants, rare and novel variants. | Pre-selected common SNPs only. Rare and novel variants are invisible. |
| Imputation | Not needed. Direct reads. | Required to estimate positions the chip did not read. |
| Reanalysis when science updates | Re-interpret the existing genome. No new sample. | Limited to positions the original chip captured. |
| Regulatory standard | Run in a CLIA-, COLA-, CAP-, and AABB-accredited lab. | Consumer-grade genotyping; clinical use needs separate validation. |
What the technology reads
Mosaic sequencing (30×)
All 3 billion base pairs across all chromosomes.
SNP arrays (consumer chips)
About 600,000 pre-selected SNP positions (about 0.02% of the genome).
How positions are selected
Mosaic sequencing (30×)
No selection. Every base is sequenced.
SNP arrays (consumer chips)
The manufacturer decides which SNPs the chip captures at design time.
Read depth
Mosaic sequencing (30×)
30×: each position is read about 30 times, so a variant call is reliable.
SNP arrays (consumer chips)
Single-pass hybridization signal; not depth-based.
Variant types detected
Mosaic sequencing (30×)
SNVs, indels, structural variants, copy-number variants, rare and novel variants.
SNP arrays (consumer chips)
Pre-selected common SNPs only. Rare and novel variants are invisible.
Imputation
Mosaic sequencing (30×)
Not needed. Direct reads.
SNP arrays (consumer chips)
Required to estimate positions the chip did not read.
Reanalysis when science updates
Mosaic sequencing (30×)
Re-interpret the existing genome. No new sample.
SNP arrays (consumer chips)
Limited to positions the original chip captured.
Regulatory standard
Mosaic sequencing (30×)
Run in a CLIA-, COLA-, CAP-, and AABB-accredited lab.
SNP arrays (consumer chips)
Consumer-grade genotyping; clinical use needs separate validation.
Mosaic vs 23andMe.
The same five minutes at home. Wildly different amounts of DNA. 23andMe’s health and trait reports run on a chip that reads about 0.02% of your genome.
| Feature | Mosaic Biodata | 23andMe |
|---|---|---|
| How much of your DNA is read | 100%: every chromosome, every gene, every variant. | About 0.02%: a SNP chip samples about 600,000 positions out of 3 billion. |
| Sequencing depth | 30× at a CLIA-, COLA-, CAP-, and AABB-accredited U.S. lab. | Single-pass SNP chip read; not depth-based. |
| Interpretation | Built and refined across 10+ years of clinical practice at Apeiron Center. | Consumer-facing ancestry and traits; limited clinically actionable depth. |
| Insights | 108 insights across nine areas of your health, plus deep-dive reports. | Varies by tier; trait- and ancestry-oriented. |
| Practitioner use | Designed to be read and defended in a clinical conversation. | Not designed for clinical use; data export possible but limited. |
| Raw data ownership | Lifetime ownership. Download your raw genome at any time. | Raw SNP data available; whole-genome data is not generated. |
| Subscription | No. One-time purchase. | Premium subscription for the more interesting features. |
| Privacy | Never sold, shared, licensed, or monetized. | Consumer privacy policy; opt-in research participation common. |
How much of your DNA is read
Mosaic Biodata
100%: every chromosome, every gene, every variant.
23andMe
About 0.02%: a SNP chip samples about 600,000 positions out of 3 billion.
Sequencing depth
Mosaic Biodata
30× at a CLIA-, COLA-, CAP-, and AABB-accredited U.S. lab.
23andMe
Single-pass SNP chip read; not depth-based.
Interpretation
Mosaic Biodata
Built and refined across 10+ years of clinical practice at Apeiron Center.
23andMe
Consumer-facing ancestry and traits; limited clinically actionable depth.
Insights
Mosaic Biodata
108 insights across nine areas of your health, plus deep-dive reports.
23andMe
Varies by tier; trait- and ancestry-oriented.
Practitioner use
Mosaic Biodata
Designed to be read and defended in a clinical conversation.
23andMe
Not designed for clinical use; data export possible but limited.
Raw data ownership
Mosaic Biodata
Lifetime ownership. Download your raw genome at any time.
23andMe
Raw SNP data available; whole-genome data is not generated.
Subscription
Mosaic Biodata
No. One-time purchase.
23andMe
Premium subscription for the more interesting features.
Privacy
Mosaic Biodata
Never sold, shared, licensed, or monetized.
23andMe
Consumer privacy policy; opt-in research participation common.
Comparison current as of September 2026.
Your Mosaic data covers every chromosome, including the variants that shape your caffeine clearance, your detox pathways, your sleep chronotype, your iron transport, and your thyroid conversion. When you are deciding whether a 3pm coffee is why your sleep is wrecked, the answer lives in positions a SNP chip never reads.
Mosaic vs Ancestry.
Built for ancestry, or built for action? Ancestry estimates are interesting once. Your DNA never changes, and a report you use for the rest of your life is a different product.
| Feature | Mosaic Biodata | Ancestry |
|---|---|---|
| Primary purpose | Your DNA for daily-life decisions: nutrition, sleep, recovery, hormones. | Ancestry estimates and family-history matching. |
| Genome coverage | 100%: whole-genome sequencing at 30× depth. | About 0.02%: a SNP chip sampling pre-selected positions. |
| Health insights | 108 insights across nine areas of your health, plus deep-dive reports. | Limited health features depending on tier and region. |
| Lab standard | CLIA-, COLA-, CAP-, and AABB-accredited U.S. lab. | High-throughput consumer genotyping; not a clinical workflow. |
| Raw data ownership | Lifetime ownership of your full raw genome. | Raw SNP data downloadable; no whole-genome data generated. |
| Future-proofing | Every future report applies to data you already have. | A new sample is the only way to capture what the chip missed. |
| Pricing model | One-time purchase. No subscription. | Lower entry price; subscription for the deeper features. |
Primary purpose
Mosaic Biodata
Your DNA for daily-life decisions: nutrition, sleep, recovery, hormones.
Ancestry
Ancestry estimates and family-history matching.
Genome coverage
Mosaic Biodata
100%: whole-genome sequencing at 30× depth.
Ancestry
About 0.02%: a SNP chip sampling pre-selected positions.
Health insights
Mosaic Biodata
108 insights across nine areas of your health, plus deep-dive reports.
Ancestry
Limited health features depending on tier and region.
Lab standard
Mosaic Biodata
CLIA-, COLA-, CAP-, and AABB-accredited U.S. lab.
Ancestry
High-throughput consumer genotyping; not a clinical workflow.
Raw data ownership
Mosaic Biodata
Lifetime ownership of your full raw genome.
Ancestry
Raw SNP data downloadable; no whole-genome data generated.
Future-proofing
Mosaic Biodata
Every future report applies to data you already have.
Ancestry
A new sample is the only way to capture what the chip missed.
Pricing model
Mosaic Biodata
One-time purchase. No subscription.
Ancestry
Lower entry price; subscription for the deeper features.
Comparison current as of September 2026.
AncestryDNA tells you where your great-great-grandparents probably lived. Mosaic tells you which foods, sleep timing, supplements, and training inputs your body tends to respond to, variant by variant. The first is a one-time look. The second is the biology you live in every day.
Read the 99.98% of your DNA they don’t.
See the real pages first. Then order your kit and every report runs on the same file.
