Section 03 of 09 • 10 insights
Macronutrients and Metabolic Optimization
You’ve tried keto, carnivore, and “everything in moderation.” None of them ever felt quite right.
There is no one-size-fits-all "perfect diet." Only the one your metabolism was built for.
From the report
The biology this section covers.
Understanding how your genetics process carbs, fats, and protein lets you build a nutrition strategy that works with your biology. This section covers how genetic variations affect your body's response to each macronutrient so that you can make smarter choices about energy, body composition, and long-term health.
The story this section tells
What your DNA is doing under the hood. Why it matters today.
Same 2,000 calories, vastly different results. Some people burn carbs efficiently; others store them immediately. Some thrive on saturated fat; others see their cholesterol rise. Your genes shape the divide.
You'll stop cycling through diets that work for others and finally discover the ratio your metabolism was truly designed for.
This one is for you if…
Every diet you've tried felt wrong—and you're beginning to think it's you, not the diet.
What you'll see in your Macronutrients and Metabolic Optimization report.
Every insight below appears as a personalized dark card in your full Mosaic report, with a color marker tuned to your specific genetic variants and a practical next step you can act on.
Saturated Fats
2 insights
macronutrients and metabolic optimization
APOE Status
Your APOE type decides how your body handles saturated fat and cholesterol. Some versions shrug off butter and steak; others see LDL spike fast. Knowing yours ends the "is saturated fat evil?" debate—for you personally.
Read insight →macronutrients and metabolic optimization
Saturated Fat Intake
Response to butter, coconut oil, and steak fat ranges from "no effect on lipids" to "major LDL jump" in different people. Your personal response ends blanket dietary dogma and lets you eat accordingly.
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Carbohydrates
2 insights
macronutrients and metabolic optimization
Fiber Benefit
Some people drop cholesterol and feel full on high-fiber meals. Others barely notice. This tells you whether loading up on oats and vegetables is a game-changer or just extra chewing.
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Ideal Carbohydrate Intake
Your genes determine whether you thrive on 45–65% carbs or feel better under 30%. Matching intake to your insulin sensitivity and carbohydrate metabolism keeps energy stable and weight easier to manage—without forcing a diet philosophy that doesn't fit your biology.
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Polyunsaturated Fat
2 insights
macronutrients and metabolic optimization
Omega-3 Intake Needs
Conversion of plant omega-3s (flax, chia, walnuts) into usable EPA/DHA varies 5–10 fold between people. Poor converters need fish or algae oil to get the brain, heart, and anti-inflammatory benefits—plants alone won't cut it.
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Omega-6 Intake Needs
Some people handle high omega-6 (seed oils, processed foods) without inflammation; others convert it into pro-inflammatory compounds fast. This tells you how strict you need to be with cooking oils—and whether the vegetable oil debate applies to you.
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For practitioners
Using Macronutrients and Metabolic Optimization in clinical practice.
Deliver the macro ratio your clients' genome actually performs best on.
About provider accounts →What to read next.
The 9 areas of your biology are interconnected: your appetite genes talk to your sleep genes, your detox pathways shape your hormone clearance. Each one informs the others.
See your macronutrients and metabolic optimization insights.
Order your kit. Receive your full 108-insight report in 15–20 days.