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What Whole Genome Sequencing Tells You That Other DNA Tests Don't

  • Feb 19
  • 2 min read

Most consumer DNA tests look at a few hundred thousand data points. That sounds like a lot until you realize your genome contains over 3 billion. Whole genome sequencing reads all of them.

So what does that actually mean for you?

Coverage matters

Standard DNA tests use a method called genotyping. They check specific, pre-selected locations on your genome — like reading every 10th word in a book. It works for some things (ancestry, a handful of health markers), but it misses a lot in between.

Whole genome sequencing reads the entire book. Every base pair, every gene, every regulatory region. And Mosaic uses 30x coverage, which means every section of your genome is read an average of 30 times for accuracy.

What this unlocks

With full sequencing, we can analyze gene variants that genotyping chips simply don't include. That means more precise insights into things like methylation efficiency, detoxification pathways, hormone metabolism, and micronutrient needs — areas where a single variant can meaningfully shift how your body works.

It also means your data doesn't expire. As the science evolves and new gene-health connections are discovered, your full genome can be re-analyzed without needing a new test.

Why CLIA certification matters here

The quality of the sequencing itself is just as important as the method. Mosaic uses a CLIA-certified lab, which means the process meets the same standards used for clinical diagnostic testing. It's the same level of rigor your doctor's lab uses — applied to your entire genome.

108 insights, one test

From that single saliva sample, Mosaic generates 108 personalized insights across 9 body systems. Everything from your caffeine metabolism to your ideal sleep duration to how your body processes estrogen. It's not a snapshot — it's a comprehensive map of your biology.

 
 
 

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